Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters

• Main Authors: Teresa Iannaccone (Author), Carmine Sellitto (Author), Valentina Manzo (Author), Francesca Colucci (Author), Valentina Giudice (Author), Berenice Stefanelli (Author), Antonio Iuliano (Author), Giulio Corrivetti (Author), Amelia Filippelli (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacogenomics can identify polymorphisms in genes involved in drug pharmacokinetics and pharmacodynamics determining differences in efficacy and safety and causing inter-individual variability in drug response. Therefore, pharmacogenomics can help clinicians in optimizing therapy based on patient...