A rare case of multiple pituitary adenomas in an adolescent Cushing disease presenting as a vertebral compression fracture

Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain, short stature, headache, and hypertension. On magnetic resonance imaging (MRI), only a...

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Main Authors: Ji-Yeon Song (Author), Sue-Jean Mun (Author), Soon-Ki Sung (Author), Jae-Yeon Hwang (Author), Seung-Kug Baik (Author), Jee Yeon Kim (Author), Chong-Kun Cheon (Author), Su-Young Kim (Author), Yoo-Mi Kim (Author)
Format: Book
Published: Korean Society of Pediatric Endocrinology, 2017-09-01T00:00:00Z.
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Summary:Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain, short stature, headache, and hypertension. On magnetic resonance imaging (MRI), only a left pituitary microadenoma was found. After surgery, transient clinical improvement was observed but headache and hypertension were observed again after 3 months later. Follow-up MRI showed a newly developed right pituitary microadenoma 6 months after the surgery. The need for careful clinical and radiographic follow-up should be emphasized in the search for potential MPAs in patients with persistent Cushing disease.
Item Description:2287-1012
2287-1292
10.6065/apem.2017.22.3.197