Recent Approaches for Solid Dose Vaccine Delivery

Recent studies on vaccine delivery systems are exploring the possibility of replacing liquid vaccines with solid dose vaccines due to the many advantages that solid dose vaccines can offer. These include the prospect of a needle-free vaccine delivery system leading to better patient compliance, cold...

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Bibliographic Details
Main Authors: Nishat Jahan (Author), Sabrina Rahman Archie (Author), Abdullah Al Shoyaib (Author), Nadia Kabir (Author), Karmen Cheung (Author)
Format: Book
Published: MDPI AG, 2019-10-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Nishat Jahan  |e author 
700 1 0 |a Sabrina Rahman Archie  |e author 
700 1 0 |a Abdullah Al Shoyaib  |e author 
700 1 0 |a Nadia Kabir  |e author 
700 1 0 |a Karmen Cheung  |e author 
245 0 0 |a Recent Approaches for Solid Dose Vaccine Delivery 
260 |b MDPI AG,   |c 2019-10-01T00:00:00Z. 
500 |a 2218-0532 
500 |a 10.3390/scipharm87040027 
520 |a Recent studies on vaccine delivery systems are exploring the possibility of replacing liquid vaccines with solid dose vaccines due to the many advantages that solid dose vaccines can offer. These include the prospect of a needle-free vaccine delivery system leading to better patient compliance, cold chain storage, less-trained vaccinators and fewer chances for needle stick injury hazards. Some studies also indicate that vaccines in a solid dosage form can result in a higher level of immunogenicity compared to the liquid form, thus providing a dose-sparing effect. This review outlines the different approaches in solid vaccine delivery using various routes of administration including, oral, pulmonary, intranasal, buccal, sublingual, and transdermal routes. The various techniques and their current advancements will provide a knowledge base for future work to be carried out in this arena. 
546 |a EN 
690 |a vaccine 
690 |a solid dose 
690 |a dose-sparing 
690 |a microneedle 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Scientia Pharmaceutica, Vol 87, Iss 4, p 27 (2019) 
787 0 |n https://www.mdpi.com/2218-0532/87/4/27 
787 0 |n https://doaj.org/toc/2218-0532 
856 4 1 |u https://doaj.org/article/8e5a2d42364b4ff6ac299ffc3b1567b9  |z Connect to this object online.