Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway
ABSTRACTObjectives Gentamicin is one of the most common ototoxic drugs that can lower patients' quality of life. Oxidative stress is a key factors inducing sensory hair cell death during gentamicin administration. So far, there are no effective drugs to prevent or treat gentamicin- induced hear...
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Main Authors: | Rui Hu (Author), Fan Wu (Author), Yi-Qing Zheng (Author) |
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Format: | Book |
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Taylor & Francis Group,
2024-12-01T00:00:00Z.
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