Metabolomic and Proteomic Profiling of Athletes Performing Physical Activity under Hypoxic Conditions
Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected from 18 male athletes performing aerobic activity (running) at high altitude. Metabolomic profiling detected changes in the levels of 4-hydro...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
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MDPI AG,
2024-03-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_8eadb7a7609446028e4fa80480f7029e | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Kristina A. Malsagova |e author |
| 700 | 1 | 0 | |a Arthur T. Kopylov |e author |
| 700 | 1 | 0 | |a Alexander A. Stepanov |e author |
| 700 | 1 | 0 | |a Liudmila I. Kulikova |e author |
| 700 | 1 | 0 | |a Alexander A. Izotov |e author |
| 700 | 1 | 0 | |a Ksenia A. Yurku |e author |
| 700 | 1 | 0 | |a Evgenii I. Balakin |e author |
| 700 | 1 | 0 | |a Vasiliy I. Pustovoyt |e author |
| 700 | 1 | 0 | |a Anna L. Kaysheva |e author |
| 245 | 0 | 0 | |a Metabolomic and Proteomic Profiling of Athletes Performing Physical Activity under Hypoxic Conditions |
| 260 | |b MDPI AG, |c 2024-03-01T00:00:00Z. | ||
| 500 | |a 10.3390/sports12030072 | ||
| 500 | |a 2075-4663 | ||
| 520 | |a Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected from 18 male athletes performing aerobic activity (running) at high altitude. Metabolomic profiling detected changes in the levels of 4-hydroxyproline, methionine, oxaloacetate, and tyrosine during the recovery period. Furthermore, proteomic profiling revealed changes in expression of proteins contributing to the function of the immune system, muscle damage, metabolic fitness and performance, as well as hemostasis. Further research should focus on developing metabolic models to monitor training intensity and athlete adaptation. | ||
| 546 | |a EN | ||
| 690 | |a metabolome | ||
| 690 | |a proteome | ||
| 690 | |a molecular profile | ||
| 690 | |a athletes | ||
| 690 | |a mass spectrometry analysis | ||
| 690 | |a Sports | ||
| 690 | |a GV557-1198.995 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Sports, Vol 12, Iss 3, p 72 (2024) | |
| 787 | 0 | |n https://www.mdpi.com/2075-4663/12/3/72 | |
| 787 | 0 | |n https://doaj.org/toc/2075-4663 | |
| 856 | 4 | 1 | |u https://doaj.org/article/8eadb7a7609446028e4fa80480f7029e |z Connect to this object online. |