Successful Treatment of Aortic Endocarditis by <i>Achromobacter xylosoxidans</i> with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

• Main Authors: Gianfranco La Bella (Author), Francesco Salvato (Author), Graziano Antonio Minafra (Author), Irene Francesca Bottalico (Author), Tiziana Rollo (Author), Lucia Barbera (Author), Samantha De Tullio (Author), Gaetano Corso (Author), Sergio Lo Caputo (Author), Rosella De Nittis (Author), Fabio Arena (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<i>Achromobacter xylosoxidans</i> is a Gram-negative aerobic opportunistic bacterium, belonging to the order of <i>Burkholderiales</i>, that can cause infections of virtually all body districts in patients with underlying diseases. However, <i>A. xylosoxidans</i> has rarely been associated with infective endocarditis. The treatment of <i>A. xylosoxidans</i> infections is complicated by both intrinsic and acquired resistance. Here we report on a case of aortic endocarditis by <i>A. xylosoxidans</i> in a Non-Hodgkin lymphoma patient treated with a combination of cefiderocol and other antibiotics, and summarize the available literature.

Item Description

10.3390/antibiotics11121686
2079-6382