TNF-alpha and insulin-resistance: metabolic effects of in vivo therapeutic blockade
Insulin resistance is a key pathophysiologic feature of obesity, type 2 diabetes mellitus and prediabetic states (impaired fasting glucose, impaired glucose tolerance). TNF-α, a proinflammatory cytokine, plays an important role in the pathogenesis of insulin resistance associated with inflammation d...
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PAGEPress Publications,
2011-06-01T00:00:00Z.
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