Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial.

• Main Authors: Monique Wasunna (Author), Simon Njenga (Author), Manica Balasegaram (Author), Neal Alexander (Author), Raymond Omollo (Author), Tansy Edwards (Author), Thomas P C Dorlo (Author), Brima Musa (Author), Mohammed Hassan Sharaf Ali (Author), Mohammed Yasein Elamin (Author), George Kirigi (Author), Rashid Juma (Author), Anke E Kip (Author), Gerard J Schoone (Author), Asrat Hailu (Author), Joseph Olobo (Author), Sally Ellis (Author), Robert Kimutai (Author), Susan Wells (Author), Eltahir Awad Gasim Khalil (Author), Nathalie Strub Wourgaft (Author), Fabiana Alves (Author), Ahmed Musa (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:SSG&PM over 17 days is recommended as first line treatment for visceral leishmaniasis in eastern Africa, but is painful and requires hospitalization. Combination regimens including AmBisome and miltefosine are safe and effective in India, but there are no published data from trials of...