Development of QCT loaded TPGS coated solid lipid nanoparticles for improved in vivo neuroprotective activity in LPS administered adult zebrafish model: A QbD-based approach

• Main Authors: Galal Mohsen Hussein Al-sayadi (Author), Gurisha Garg (Author), Arti Singh (Author), Preeti Patel (Author), Ghanshyam Das Gupta (Author), Balak Das Kurmi (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work contains the development of QCT-loaded TPGS-coated SLNs by QbD to enhance neuroinflammation potential. Developed SLNs were in the nanometer range (263±3.62 nm) with desired parameters i.e., PDI (0.244±0.003), zeta potential (28.2 ± 0.74 mV), and%EE (74.3 ± 2.45 %) respectively. The release...