Cover Image

Chaihu and Longgu Muli Decoction demonstrate neuroprotective effects in the rat model of Parkinson's disease with depression by regulating the AMPK/mTOR signaling pathway

Background: Chaihu and Longgu Muli decoction (CLMD) has been used as a classical prescription of traditional Chinese medicine (TCM) prescription to treat Parkinson's disease with depression (PDD). Nevertheless, the potential mechanisms underlying their neuroprotective effects are not well-under...

Full description

Saved in:

Bibliographic Details
Main Authors:	Wei Liu (Author), Junling Cao (Author), Jingfeng Ouyang (Author), Mengxia Yin (Author), Tuotuo Cui (Author), Xin Liu (Author), Yujuan Li (Author), Ying Huang (Author), Zhiwei Jing (Author)
Format:	Book
Published:	Elsevier, 2023-05-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice
by: Xing Wang, et al.
Published: (2019)

Effect-enhancing and toxicity-reducing effects of Chaihu Jia Longgu Muli decoction in the treatment of multimorbidity with depression: a systematic review and meta-analysis
by: Xurui Jia, et al.
Published: (2023)

The pharmacological mechanism of chaihu-jia-longgu-muli-tang for treating depression: integrated meta-analysis and network pharmacology analysis
by: Yang Zhao, et al.
Published: (2023)

Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway
by: Lihua Cui, et al.
Published: (2021)

The AMPK-mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis
by: Zheng Liang, et al.
Published: (2024)

Microbiota-derived tryptophan metabolism and AMPK/mTOR pathway mediate antidepressant-like effect of Shugan Hewei Decoction
by: Yingying Yue, et al.
Published: (2024)

Danggui Shaoyao San and disassembled prescription: neuroprotective effects via AMPK/mTOR-mediated autophagy in mice
by: Xiaoqing Cheng, et al.
Published: (2024)

Kun-Dan Decoction Ameliorates Insulin Resistance by Activating AMPK/mTOR-Mediated Autophagy in High-Fat Diet-Fed Rats
by: Zuqing Su, et al.
Published: (2021)

Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway
by: Xiangjin Zheng, et al.
Published: (2021)

Protective effect of omega-3 polyunsaturated fatty acids on sepsis via the AMPK/mTOR pathway
by: Peng Liu, et al.
Published: (2023)

Trimetazidine ameliorates sunitinib-induced cardiotoxicity in mice via the AMPK/mTOR/autophagy pathway
by: Yi Yang, et al.
Published: (2019)

Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway
by: Wu T, et al.
Published: (2015)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
by: Liuran Li, et al.
Published: (2021)

Immunomodulatory and Antiaging Mechanisms of Resveratrol, Rapamycin, and Metformin: Focus on mTOR and AMPK Signaling Networks
by: Vincenzo Sorrenti, et al.
Published: (2022)

Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways
by: Ting Chen, et al.
Published: (2023)

Metformin Potentiates the Effects of Anlotinib in NSCLC via AMPK/mTOR and ROS-Mediated Signaling Pathways
by: Zhongling Zhu, et al.
Published: (2021)

Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Pancreatic Cancer by Inducing Autophagy Through AMPK/mTOR Pathway
by: Xiao Li, et al.
Published: (2019)

Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway
by: Zhang S, et al.
Published: (2018)

The protective roles of allicin on type 1 diabetes mellitus through AMPK/mTOR mediated autophagy pathway
by: Rengcheng Qian, et al.
Published: (2023)

O304 alleviates abdominal aortic aneurysm formation via AMPK/mTOR/MMP pathway activation
by: Daohan Sun, et al.
Published: (2024)

Metformin Attenuates Silica-Induced Pulmonary Fibrosis by Activating Autophagy via the AMPK-mTOR Signaling Pathway
by: Shu-xian Li, et al.
Published: (2021)

Cigarette smoke exposure induces ROS-mediated autophagy by regulating sestrin, AMPK, and mTOR level in mice
by: Ana Lucia Bernardo Carvalho Morsch, et al.
Published: (2019)

Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway
by: Jie Zheng, et al.
Published: (2021)

Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway
by: Xiaoyu Liu, et al.
Published: (2021)

Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling
by: Yanan Wang, et al.
Published: (2024)

BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain-Implications for Neurodegeneration
by: Chiara Lanzillotta, et al.
Published: (2020)

Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells
by: Na Qu, et al.
Published: (2022)

Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis
by: You G, et al.
Published: (2020)

Ammidin ameliorates myocardial hypoxia/reoxygenation injury by inhibiting the ACSL4/AMPK/mTOR-mediated ferroptosis pathway
by: Yue Han, et al.
Published: (2023)

mTOR in Human Diseases
by: Dormond, Olivier
Published: (2019)

Zhen-Wu-Tang Induced Mitophagy to Protect Mitochondrial Function in Chronic Glomerulonephritis via PI3K/AKT/mTOR and AMPK Pathways
by: Bihao Liu, et al.
Published: (2021)

Ferulic acid suppresses the inflammation and apoptosis in Kawasaki disease through activating the AMPK/mTOR/NF-κB pathway
by: Huilan Wu, et al.
Published: (2024)

Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain
by: Tillu Dipti V, et al.
Published: (2012)

Irisin Ameliorates PM2.5-Induced Acute Lung Injury by Regulation of Autophagy Through AMPK/mTOR Pathway
by: Ma J, et al.
Published: (2023)

Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
by: Xiao Yan Liu, et al.
Published: (2022)

The efficacy of Da Chaihu decoction combined with metformin tablets for type 2 diabetes mellitus: A systematic review and meta-analysis
by: Jia-bin Wang, et al.
Published: (2022)

Chaihu-Guizhi-Ganjiang Decoction is more efficacious in treating irritable bowel syndrome than Dicetel according to metabolomics analysis
by: Mingming Li, et al.
Published: (2022)

Qianlie Xiaozheng Decoction Induces Autophagy in Human Prostate Cancer Cells via Inhibition of the Akt/mTOR Pathway
by: Yuehua Xu, et al.
Published: (2018)

mTOR Signaling in Metabolism and Cancer
Published: (2020)

Dorsal Root Ganglion Maintains Stemness of Bone Marrow Mesenchymal Stem Cells by Enhancing Autophagy through the AMPK/mTOR Pathway in a Coculture System
by: Shuaishuai Zhang, et al.
Published: (2018)