Hepatic Anti-Oxidative Genes <i>CAT</i> and <i>GPX4</i> Are Epigenetically Modulated by RORγ/NRF2 in Alphacoronavirus-Exposed Piglets

• Main Authors: Haotian Gu (Author), Yaya Liu (Author), Yahui Zhao (Author), Huan Qu (Author), Yanhua Li (Author), Abdelkareem A. Ahmed (Author), Hao-Yu Liu (Author), Ping Hu (Author), Demin Cai (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a member of alpha-coronaviruses, PEDV could lead to severe diarrhea and dehydration in newborn piglets. Given that lipid peroxides in the liver are key mediators of cell proliferation and death, the role and regulation of endogenous lipid peroxide metabolism in response to coronavirus infection n...