Investigation of Angiogenesis and Wound Healing Potential Mechanisms of Zinc Oxide Nanorods

The angiogenesis process is an essential issue in tissue engineering. Zinc oxide nanorods are biocompatible metals capable of generating reactive oxygen species (ROS) that respond to induced angiogenesis through various mechanisms; however, released Zn (II) ions suppress the angiogenesis process. In...

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Bibliographic Details
Main Authors: Amr Hassan (Author), Dalia Elebeedy (Author), Emadeldin R. Matar (Author), Aly Fahmy Mohamed Elsayed (Author), Ahmed I. Abd El Maksoud (Author)
Format: Book
Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
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100 1 0 |a Amr Hassan  |e author 
700 1 0 |a Dalia Elebeedy  |e author 
700 1 0 |a Emadeldin R. Matar  |e author 
700 1 0 |a Aly Fahmy Mohamed Elsayed  |e author 
700 1 0 |a Ahmed I. Abd El Maksoud  |e author 
700 1 0 |a Ahmed I. Abd El Maksoud  |e author 
245 0 0 |a Investigation of Angiogenesis and Wound Healing Potential Mechanisms of Zinc Oxide Nanorods 
260 |b Frontiers Media S.A.,   |c 2021-10-01T00:00:00Z. 
500 |a 1663-9812 
500 |a 10.3389/fphar.2021.661217 
520 |a The angiogenesis process is an essential issue in tissue engineering. Zinc oxide nanorods are biocompatible metals capable of generating reactive oxygen species (ROS) that respond to induced angiogenesis through various mechanisms; however, released Zn (II) ions suppress the angiogenesis process. In this study, we fabricated green ZnO nanorods using albumin eggshell as a bio-template and investigate its angiogenic potential through chorioallantoic membrane assay and excision wound healing assay. This study demonstrated that angiogenesis and wound healing processes depend on pro-angiogenic factors as VEGF expression due to ZnO nanorods' exiting. Angiogenesis induced via zinc oxide nanorods may develop sophisticated materials to apply in the wound healing field. 
546 |a EN 
690 |a zinc oxide nanorods 
690 |a angiogenesis 
690 |a wound healing 
690 |a VEGF 
690 |a ROS 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pharmacology, Vol 12 (2021) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fphar.2021.661217/full 
787 0 |n https://doaj.org/toc/1663-9812 
856 4 1 |u https://doaj.org/article/8f64c9a292f846519d34c5e9cbe6dc4d  |z Connect to this object online.