The application of ecologically acceptable concept in liquid chromatographic method development in drug analyses
Liquid chromatography is the most widely used analytical technique in course of research and development, as well as for routine investigation and quality control of pharmaceutical products. Having in mind the remarkable amount of waist resulting from the use of organic solvents, especially for reve...
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| Main Authors: | , , , |
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| Format: | Book |
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Pharmaceutical Association of Serbia, Belgrade, Serbia,
2015-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Liquid chromatography is the most widely used analytical technique in course of research and development, as well as for routine investigation and quality control of pharmaceutical products. Having in mind the remarkable amount of waist resulting from the use of organic solvents, especially for reversed-phase liquid chromatography, recently ecologically acceptable concepts in chromatographic method development were noticed. The 3 Rrule (Reduce - Replace - Recycle) refers to the decrease of the toxic solvents use, their replacement with less toxic ones and the use of renewable solvents. This paper presents different solutions commonly applied in drug analysis that are in accordance with the 3 Rrule. |
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| Item Description: | 0004-1963 2217-8767 10.5937/arhfarm1503178O |