The application of ecologically acceptable concept in liquid chromatographic method development in drug analyses

Liquid chromatography is the most widely used analytical technique in course of research and development, as well as for routine investigation and quality control of pharmaceutical products. Having in mind the remarkable amount of waist resulting from the use of organic solvents, especially for reve...

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Main Authors: Otašević Biljana (Author), Protić Ana (Author), Golubović Jelena (Author), Zečević Mira (Author)
Format: Book
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2015-01-01T00:00:00Z.
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700 1 0 |a Golubović Jelena  |e author 
700 1 0 |a Zečević Mira  |e author 
245 0 0 |a The application of ecologically acceptable concept in liquid chromatographic method development in drug analyses 
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520 |a Liquid chromatography is the most widely used analytical technique in course of research and development, as well as for routine investigation and quality control of pharmaceutical products. Having in mind the remarkable amount of waist resulting from the use of organic solvents, especially for reversed-phase liquid chromatography, recently ecologically acceptable concepts in chromatographic method development were noticed. The 3 Rrule (Reduce - Replace - Recycle) refers to the decrease of the toxic solvents use, their replacement with less toxic ones and the use of renewable solvents. This paper presents different solutions commonly applied in drug analysis that are in accordance with the 3 Rrule. 
546 |a SR 
690 |a drug analysis 
690 |a liquid chromatography 
690 |a the use of organic solvents 
690 |a ecologically acceptable solutions 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Arhiv za farmaciju, Vol 65, Iss 3, Pp 178-190 (2015) 
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787 0 |n https://doaj.org/toc/2217-8767 
856 4 1 |u https://doaj.org/article/8f6bfa9fa1d94df0aff3ba8cd3647130  |z Connect to this object online.