Prevalence of Cefepime-Resistant Escherichia coli in Iran: A Meta-Analysis (2007-2016)

Background: Cefepime-resistant Escherichia coli (E. coli) is one of the seven important types of microbial resistance. This meta-analysis study was conducted to identify the prevalence of cefepime-resistant E. coli in Iran during 2007-2016. Methods: Studies published were searched in Persian databas...

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Main Authors: Seyyede Maryam BECHASHK (Author), Ghobad MORADI (Author), Behzad MOHSENPOUR (Author), Rashid RAMAZANZADEH (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2019-04-01T00:00:00Z.
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LEADER 00000 am a22000003u 4500
001 doaj_8f8c1bae92d547e5834c4c2b88c50e23
042 |a dc 
100 1 0 |a Seyyede Maryam BECHASHK  |e author 
700 1 0 |a Ghobad MORADI  |e author 
700 1 0 |a Behzad MOHSENPOUR  |e author 
700 1 0 |a Rashid RAMAZANZADEH  |e author 
245 0 0 |a Prevalence of Cefepime-Resistant Escherichia coli in Iran: A Meta-Analysis (2007-2016) 
260 |b Tehran University of Medical Sciences,   |c 2019-04-01T00:00:00Z. 
500 |a 10.18502/ijph.v48i4.981 
500 |a 2251-6085 
500 |a 2251-6093 
520 |a Background: Cefepime-resistant Escherichia coli (E. coli) is one of the seven important types of microbial resistance. This meta-analysis study was conducted to identify the prevalence of cefepime-resistant E. coli in Iran during 2007-2016. Methods: Studies published were searched in Persian databases (including Magiran, and SID) and international databases (including PubMed, ScienceDirect, and Scopus). The selected studies included all types of laboratory methods. Moreover, the random effects model (DerSimonian Laird method) was used to addresses the high heterogeneity (50% < I2) between the reviewed studies. The collected data were categorized into different subgroups on the basis of the year of study and province. Data analysis was performed using the Statsdirect software. Results: Overall, 516 articles were selected from the searched medical databases. After reviewing and applying the inclusion criteria, irrelevant papers were excluded and the remaining 26 studies were meta-analyzed. The overall prevalence of cefepime-resistant E. coli was 53.42% (95%: 43.35, 63.35), ranging from 25% (95%CI: 21.67, 28.55) in 2009 to 61.95% (95%CI: 56.62, 67.09) in 2016. Conclusion: The prevalence of cefepime-resistant E. coli in Iran has had an increasing and alarming trend during the recent years. Therefore, it is necessary to use practical strategies and interventions to control and monitor cefepime-resistant E. coli in the country. 
546 |a EN 
690 |a Prevalence 
690 |a Antimicrobial resistance 
690 |a Escherichia coli 
690 |a Cefepime 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Iranian Journal of Public Health, Vol 48, Iss 4 (2019) 
787 0 |n https://ijph.tums.ac.ir/index.php/ijph/article/view/16850 
787 0 |n https://doaj.org/toc/2251-6085 
787 0 |n https://doaj.org/toc/2251-6093 
856 4 1 |u https://doaj.org/article/8f8c1bae92d547e5834c4c2b88c50e23  |z Connect to this object online.