Phytochemical Composition and In Vitro Antimicrobial Activity of Essential Oils from the <i>Lamiaceae</i> Family against <i>Streptococcus agalactiae</i> and <i>Candida albicans</i> Biofilms

• Main Authors: Ramona Iseppi (Author), Roberta Tardugno (Author), Virginia Brighenti (Author), Stefania Benvenuti (Author), Carla Sabia (Author), Federica Pellati (Author), Patrizia Messi (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

The antimicrobial activity of different essential oils (EOs) from the <i>Lamiaceae</i> family was evaluated on <i>Streptococcus agalactiae</i>, <i>Candida albicans</i>, and lactobacilli. <i>S. agalactiae</i> is the main cause of severe neonatal infections, such as sepsis, meningitis, and pneumonia. <i>C. albicans</i> is a primary causative agent of vulvovaginal candidiasis, a multifactorial infectious disease of the lower female reproductive tract. Lactobacilli represent the dominant bacterial species of the vaginal flora and constitute the natural defense against pathogens. On the basis of the preliminary results, the attention was focused on the EOs from <i>Lavandula x intermedia</i> Emeric ex Loisel. and <i>Mentha arvensis</i> L. By using gas ghromatography (GS) retention data and mass spectra, it was possible to identify more than 90% of the total composition of the EO samples. The minimal inhibitory concentration (MIC) and anti-biofilm activity of the two EOs were determined against all isolated strains, using the EOs by themselves or in combination with each other and with drugs (erythromycin and fluconazole). The results showed a good antimicrobial and anti-biofilm activity of both EOs and a synergistic effect, leading to the best results against all the strains, resulted using the combinations EOs/EOs and antimicrobials/EOs.

Item Description

10.3390/antibiotics9090592
2079-6382