Clinicopathological characteristics and management of extramedullary hematopoiesis: A review
Extramedullary hematopoiesis (EMH) is a rare entity most often associated with primary myelofibrosis, chronic myeloproliferative neoplasms, chronic hemolytic states, such as thalassemia, sickle cell anemia and certain solid tumors. Various theories have been postulated as the mechanism for occurrenc...
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| Main Authors: | , , , , |
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| Format: | Book |
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Elsevier,
2022-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Extramedullary hematopoiesis (EMH) is a rare entity most often associated with primary myelofibrosis, chronic myeloproliferative neoplasms, chronic hemolytic states, such as thalassemia, sickle cell anemia and certain solid tumors. Various theories have been postulated as the mechanism for occurrence of EMH. Iron deposition and/or fatty infiltration along with increased density of liver and spleen may be observed on imaging. Also, organs may show diffuse involvement or mass like foci of hematopoiesis on imaging. Treatment includes transfusion, surgery, hydroxyurea and radiation. In this review we narrate the clinicopathological features, radiological imaging and treatment strategies of non hepatosplenic Extramedullary hematopoiesis. |
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| Item Description: | 2468-1245 10.1016/j.phoj.2022.11.001 |