Benzonate derivatives of acetophenone as potent α-glucosidase inhibitors: synthesis, structure-activity relationship and mechanism
In this article, 23 compounds (6 and 7a-7v) were prepared and evaluated for their in vitro α-glucosidase inhibitory activity. The compounds 7d, 7f, 7i, 7n, 7o, 7r, 7s, 7u, and 7v displayed the α-glucosidase inhibition activity with IC50 values ranging from 1.68 to 7.88 µM. Among all tested compounds...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2019-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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