The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

• Hauptverfasser: Hafiza Bushra Manzoor (Verfasst von), Meshach Asare-Werehene (Verfasst von), Satyajit Dey Pereira (Verfasst von), Kapaettu Satyamoorthy (Verfasst von), Benjamin K. Tsang (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2024-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...