The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

• Autores principales: Hafiza Bushra Manzoor (Autor), Meshach Asare-Werehene (Autor), Satyajit Dey Pereira (Autor), Kapaettu Satyamoorthy (Autor), Benjamin K. Tsang (Autor)
• Formato: Libro
• Publicado: BMC, 2024-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...