The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

• मुख्य लेखकों: Hafiza Bushra Manzoor (लेखक), Meshach Asare-Werehene (लेखक), Satyajit Dey Pereira (लेखक), Kapaettu Satyamoorthy (लेखक), Benjamin K. Tsang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...