The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

• Autori principali: Hafiza Bushra Manzoor (Autore), Meshach Asare-Werehene (Autore), Satyajit Dey Pereira (Autore), Kapaettu Satyamoorthy (Autore), Benjamin K. Tsang (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2024-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...