The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

• Главные авторы: Hafiza Bushra Manzoor (Автор), Meshach Asare-Werehene (Автор), Satyajit Dey Pereira (Автор), Kapaettu Satyamoorthy (Автор), Benjamin K. Tsang (Автор)
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• Опубликовано: BMC, 2024-01-01T00:00:00Z.
• Предметы: article
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Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...