Stroke in a child with hemoglobin SC disease: a case report describing use of hydroxyurea after transfusion therapy
Children with hemoglobin SC (HbSC) disease suffer a significant incidence of silent cerebral infarcts but stroke is rare. A 2-year-old African American boy with HbSC disease presented with focal neurologic deficits associated with magnetic resonance imaging evidence of cerebral infarction with vascu...
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| Main Authors: | , , , , |
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| Format: | Book |
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MDPI AG,
2017-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Children with hemoglobin SC (HbSC) disease suffer a significant incidence of silent cerebral infarcts but stroke is rare. A 2-year-old African American boy with HbSC disease presented with focal neurologic deficits associated with magnetic resonance imaging evidence of cerebral infarction with vascular abnormalities. After the acute episode he was treated with monthly transfusions and subsequently transitioned to hydroxyurea therapy. The benefits of hydroxyurea as a fetal hemoglobin inducer in HbSC disease, to ameliorate clinical symptoms are supported by retrospective studies. This case highlights the rare occurrence of stroke in a child with HbSC disease and the use of hydroxyurea therapy. |
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| Item Description: | 2036-749X 2036-7503 10.4081/pr.2017.6984 |