Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer
ClpP activators ONC201 and related small molecules (TR compounds, Madera Therapeutics), have demonstrated significant anti-cancer potential in vitro and in vivo studies, including clinical trials for refractory solid tumors. Though progress has been made in identifying specific phenotypic outcomes f...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2023-03-01T00:00:00Z.
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