Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats

• मुख्य लेखकों: Raylene A. Reimer (लेखक), Jeremy M. LaMothe (लेखक), Ronald F. Zernicke (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2012-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Leptin signaling deficient rodents have emerged as models of obesity/insulin resistance syndrome. Altered leptin signaling, however, can affect axial and appendicular bone geometrical properties differently, and, thus, we hypothesized that leptin-deficiency would differentially influence mechanical...