Cover Image

Development of Bedaquiline-Loaded SNEDDS Using Quality by Design (QbD) Approach to Improve Biopharmaceutical Attributes for the Management of Multidrug-Resistant Tuberculosis (MDR-TB)

<b>Background:</b> The ever-growing emergence of antibiotic resistance associated with tuberculosis (TB) has become a global challenge. In 2012, the USFDA gave expedited approval to bedaquiline (BDQ) as a new treatment for drug-resistant TB in adults when no other viable options are avai...

Full description

Saved in:

Bibliographic Details
Main Authors:	Rao Nargis Jahan (Author), Zafar Khan (Author), Md. Sayeed Akhtar (Author), Mohd Danish Ansari (Author), Pavitra Solanki (Author), Farhan J. Ahmad (Author), Mohd Aqil (Author), Yasmin Sultana (Author)
Format:	Book
Published:	MDPI AG, 2023-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Cost-effectiveness of bedaquiline in MDR and XDR tuberculosis in Italy
by: Luigi R. Codecasa, et al.
Published: (2017)

Applications of quality by design (QbD) and its tools in drug delivery
by: Lan Zhang, et al.
Published: (2016)

QbD approach to HPLC method development and validation of ceftriaxone sodium
by: Krunal Y. Patel, et al.
Published: (2021)

Ensuring Pharmaceutical Product Success through Excipient QbD Efforts
by: Mohammad Siddique Qadir
Published: (2022)

Compression-coated pulsatile chronomodulated therapeutic system: QbD assisted optimization
by: Hibah M. Aldawsari, et al.
Published: (2022)

An Updated Risk Assessment as Part of the QbD-Based Liposome Design and Development
by: Zsófia Németh, et al.
Published: (2021)

Extraction process in Chuantieling (CTL) based on the quality by design (QbD) concept
by: Li Ya, et al.
Published: (2022)

Satisfying QTPP of Erythropoietin Biosimilar by QbD through DoE-Derived Downstream Process Engineering
by: Kakon Nag, et al.
Published: (2023)

Design of Experiments (DoE) applied to Pharmaceutical and Analytical Quality by Design (QbD)
by: Isa Martins Fukuda, et al.
Published: (2018)

Quality by Design (QbD) como ferramenta para otimização dos processos farmacêuticos
by: Mariana Palmeira BEZERRA, et al.
Published: (2017)

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach
by: Nawaf Almotairi, et al.
Published: (2022)

Development and validation of a QbD-based RP-HPLC method for vericiguat quantification
by: Shubham Mandhare, et al.
Published: (2024)

An industrial case study: QbD to accelerate time-to-market of a drug product
by: Madalena Testas, et al.
Published: (2021)

QbD-guided phospholipid-tagged nanonized boswellic acid naturosomal delivery for effective rheumatoid arthritis treatment
by: Poonam Usapkar, et al.
Published: (2024)

Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product
by: Jonas Pielenhofer, et al.
Published: (2023)

QbD-Based Investigation of Dermal Semisolid in situ Film-Forming Systems for Local Anaesthesia
by: Kovács A, et al.
Published: (2020)

Industrial application of QbD and NIR chemometric models in quality improvement of immediate release tablets
by: Ahmed Ramadan, et al.
Published: (2021)

Design Space and QbD Approach for Production of Drug Nanocrystals by Wet Media Milling Techniques
by: Leena Peltonen
Published: (2018)

QbD driven targeted pulmonary delivery of dexamethasone-loaded chitosan microspheres: Biodistribution and pharmacokinetic study
by: B.R. Asha, et al.
Published: (2023)

Preparation of Ibuprofen-Loaded Inhalable γCD-MOFs by Freeze-Drying Using the QbD Approach
by: Anett Motzwickler-Németh, et al.
Published: (2024)

Fluidised bed granulation of two APIs: QbD approach and development of a NIR in-line monitoring method
by: Alexandru Gavan, et al.
Published: (2020)

Solubility enhancement of etoricoxib using inclusion complexation with cyclodextrins: formulation of oro dispersible tablets by QbD approach
by: Anjan Kumar Mahapatra, et al.
Published: (2024)

Development of Metronidazole Loaded Chitosan Nanoparticles Using QbD Approach-A Novel and Potential Antibacterial Formulation
by: Nagaraja Sreeharsha, et al.
Published: (2020)

Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies
by: Waleed Y. Rizg, et al.
Published: (2022)

The Use of the QbD Approach to Optimize the Co-Loading of Simvastatin and Doxorubicin in Liposomes for a Synergistic Anticancer Effect
by: Cristina-Ioana Barbalata, et al.
Published: (2022)

QbD Consideration for Developing a Double-Layered Tablet into a Single-Layered Tablet with Telmisartan and Amlodipine
by: Joo-Eun Kim, et al.
Published: (2022)

Gamma oryzanol niosomal gel for skin cancer: formulation and optimization using quality by design (QbD) approach
by: Harsh S. Shah, et al.
Published: (2021)

QbD-based design and characterization of mucoadhesive microspheres of quetiapine fumarate with improved oral bioavailability and brain biodistribution potential
by: Someshwar Komati, et al.
Published: (2018)

Optimization of the Micellar-Based In Situ Gelling Systems Posaconazole with Quality by Design (QbD) Approach and Characterization by In Vitro Studies
by: Meltem Ezgi Durgun, et al.
Published: (2022)

A QbD Approach for Evaluating the Effect of Selective Laser Sintering Parameters on Printability and Properties of Solid Oral Forms
by: Yanis A. Gueche, et al.
Published: (2021)

Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC
by: Mousa Sha'at, et al.
Published: (2022)

Nanoemulsion drug delivery system loaded with imiquimod: a QbD-based strategy for augmenting anti-cancer effects
by: Shital Tanaji Jadhav, et al.
Published: (2023)

Evaluations of Quality by Design (QbD) Elements Impact for Developing Niosomes as a Promising Topical Drug Delivery Platform
by: Parinbhai Shah, et al.
Published: (2020)

QbD-Based Development and Evaluation of Pazopanib Hydrochloride Extrudates Prepared by Hot-Melt Extrusion Technique: In Vitro and In Vivo Evaluation
by: Amit Gupta, et al.
Published: (2024)

Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets
by: Farooqi S, et al.
Published: (2020)

A Cost Effective (QbD) Approach in the Development and Optimization of Rosiglitazone Maleate Mucoadhesive Extended Release Tablets - In Vitro and Ex Vivo
by: Suryaprakash Reddy Chappidi, et al.
Published: (2019)

QbD enabled Process Variable Study to Develop Sustained Release Chitosan-Alginate Embedded Delivery System for Improved Patient Compliance
by: Vijay Sharma, et al.
Published: (2022)

Continuous twin screw granulation: Impact of microcrystalline cellulose batch-to-batch variability during granulation and drying - A QbD approach
by: Christoph Portier, et al.
Published: (2021)

Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation
by: Mahipal Reddy Donthi, et al.
Published: (2023)

Fixed Dose Single Tablet Formulation with Differential Release of Amlodipine Besylate and Simvastatin and Its Pharmacokinetic Profile: QbD and Risk Assessment Approach
by: Kanwal U, et al.
Published: (2021)