Clinical Relevance of Faecal Calprotectin Level in Infantile Colic: A Cross-sectional Survey

Background: There is limited knowledge on the potential applicability of fecal calprotectin (f-CP) as an inflammatory screening parameter in infantile colic (IC). This study aimed to evaluate f-CP in neonates with IC as a useful diagnostic indicator regarding this condition. Methods: The present stu...

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Main Authors: Iraj Shahramian (Author), Ali Bazi (Author), Alireza Sargazi (Author), Omolbanin Sargazi Aval (Author), Alireza Dechal (Author), Mostafa Bazzi (Author), Masoud Jahantigh (Author)
Format: Book
Published: Mashhad University of Medical Sciences, 2018-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Iraj Shahramian  |e author 
700 1 0 |a Ali Bazi  |e author 
700 1 0 |a Alireza Sargazi  |e author 
700 1 0 |a Omolbanin Sargazi Aval  |e author 
700 1 0 |a Alireza Dechal  |e author 
700 1 0 |a Mostafa Bazzi  |e author 
700 1 0 |a Masoud Jahantigh  |e author 
245 0 0 |a Clinical Relevance of Faecal Calprotectin Level in Infantile Colic: A Cross-sectional Survey 
260 |b Mashhad University of Medical Sciences,   |c 2018-12-01T00:00:00Z. 
500 |a 2251-7510 
500 |a 2322-2158 
500 |a 10.22038/ijn.2018.11905 
520 |a Background: There is limited knowledge on the potential applicability of fecal calprotectin (f-CP) as an inflammatory screening parameter in infantile colic (IC). This study aimed to evaluate f-CP in neonates with IC as a useful diagnostic indicator regarding this condition. Methods: The present study was conducted on 100 cases, including 50 newborns with IC and 50 non-colicky neonates. The diagnosis of IC was fulfilled by the Wessel Criteria. The level of f-CP was determined by a specific enzyme-linked immunosorbent assay kit (Calprotectin ELISA, EuroImmun, Germany). The statistical analysis was performed in SPSS software (version 19).   Results: Out of 100 neonates, 57 cases were male and 43 subjects were female. The age spectrum ranged from 19-90 days (40.4±15.9). Colicky newborns were slightly younger (P=0.06) with higher birth weight compared to the infants without colic (P 
546 |a EN 
690 |a Keywords: Calprotectin 
690 |a Infantile colic 
690 |a Intestinal inflammation 
690 |a Leukocyte L1 antigen complex 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Iranian Journal of Neonatology, Vol 9, Iss 4, Pp 66-71 (2018) 
787 0 |n http://ijn.mums.ac.ir/article_11905_ac09e440c18591fb8e874165781e3329.pdf 
787 0 |n https://doaj.org/toc/2251-7510 
787 0 |n https://doaj.org/toc/2322-2158 
856 4 1 |u https://doaj.org/article/9038d8e5ce1e46418c5c1e40a43d3af7  |z Connect to this object online.