Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface
<p>Abstract</p> <p>The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover re...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
BMC,
2003-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | <p>Abstract</p> <p>The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune system at the feto-maternal interface, citing examples of the role played by microbial infections in fetal demise.</p> |
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| Item Description: | 10.1186/1477-7827-1-121 1477-7827 |