Effect of Fish Oil on Serum Levels of Lipid Profile, Lipoprotein (a), Apolipoprotein A-1 and B, Fasting Sugar and Insulin, and InsulinResistance in the Elderly Residents of Kahrizak Charity Foundation

• Main Authors: Hossein Fakhrzadeh (Author), Maryam Ghaderpanahi (Author), Farshad Sharifi (Author), Ahmad Ali AkbariKamrani (Author), Zohre Badamchizade (Author), Bagher Larijani (Author)
• Format: Book
• Published: University of Social Welfare & Rehabilitation Sciences, 2010-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1735-806X; 1735-806X
• Keywords: Fish oil; Omega-3 Fatty Acids; Apolipoproteins; Blood sugar; Insulin resistance; Aged; Geriatrics; RC952-954.6; Public aspects of medicine; RA1-1270
• Source: Sālmand, Vol 4, Iss 2, Pp 0-0 (2010)

Objectives: This study was performed to investigate the effect of ω-3 fatty acids on lipid profiles, lipoprotein (a), apolipoprotein A-1 and apolipoprotein B, fasting glucose and insulin, and insulin resistance in a group of Iranian elderly subjects. Methods & Materials: In this clinical trial, 124 elderly residents of the KahrizakCharity Foundation, aged 65 and older were divided into two intervention (consumption of 1 gram per day of fish oil) and control (consumption of placebo) groups. Blood sampling was done at the baseline and at the end of the study. Results: After 6 months, TG and apo A-1 increased significantly (P=0.01 and P=0.02, respectively) and high-density lipoprotein cholesterol decreased significantly in the control group (P=0.009). Overall and comparative effects of fish oil were positively significant (P=0.02). Conclusion: fish oil intake can be effective in reduction of serumtriglycerides in elderly.