Clinical features of children with retinoblastoma in Adam Malik Hospital, Medan, Indonesia

• Main Author: Bidasari Lubis (Author)
• Format: Book
• Published: Indonesian Pediatric Society Publishing House, 2001-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0030-9311; 2338-476X; 10.14238/pi41.5.2001.234-6
• Keywords: retinoblastoma; diagnosis; clinical features; prognosis; Medicine; R; Pediatrics; RJ1-570
• Source: Paediatrica Indonesiana, Vol 41, Iss 5, Pp 234-6 (2001)

We reviewed patents with retinoblastoma treated at the Department of Child Health, Adam Malik Hospital, Medan from January 1995 to December 1999. Clinical staging was based on Reese-Ellsworth classification (when the disease was limited to the eyeball) or on St Jude Children's Research Hospital (when the disease has extended beyond the eyeball). A total 19 retinoblastoma patients were available, from which 9 were males. Fifteen patients were less than 5 years old, and the average age at diagnosis was 3 years 8 months. In most patients the disease started at the age of less than 5 years, and they presented themselves with advanced stage as usually seen in developing countries. In nine patients the retinoblastoma affected the right eye, 8 affected the left eye, and in 2 patients the tumor was bilateral. The most common presenting symptom on admission was proptosis. Pathological confirmation was obtained in all patients. Bone marrow puncture was done in 15 patients; of whom 13 showed bone marrow metastasis. Since 1998 the standard treatment for patients with proptosis in stage III or IV of the disease was pre-operative chemotherapy followed by enucleation, radiation and chemotherapy.