Severe sepsis caused by serious gastrointestinal infection in sJIA patients treated with IL-6 receptor antagonist: a case report

• المؤلفون الرئيسيون: Meng Xu (مؤلف), Congcong Liu (مؤلف), Lishuang Guo (مؤلف), Sirui Yang (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2020-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Interleukin (IL)-6 plays an essential role in the pathogenesis of systemic juvenile idiopathic arthritis (sJIA). Tocilizumab (TCZ), a kind of biological agent against both membrane and soluble IL-6 receptor, is the only biological agent approved for the treatment of sJIA in China...