Discovery of caffeoylisocitric acid as a Keap1-dependent Nrf2 activator and its effects in mesangial cells under high glucose

• Автори: Huankai Yao (Автор), Wenting Zhang (Автор), Feng Yang (Автор), Fengwei Ai (Автор), Dan Du (Автор), Yan Li (Автор)
• Формат: Книга
• Опубліковано: Taylor & Francis Group, 2022-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Diabetic nephropathy (DN) is one of the severe microvascular complications of diabetes mellitus. Oxidative stress resulting from aberrant metabolism of glucose mediates renal inflammation and fibrosis in the progression of DN. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription fac...