Molecular characterization of severin from Clonorchis sinensis excretory/secretory products and its potential anti-apoptotic role in hepatocarcinoma PLC cells.

• Main Authors: Xueqing Chen (Author), Shan Li (Author), Lei He (Author), Xiaoyun Wang (Author), Pei Liang (Author), Wenjun Chen (Author), Meng Bian (Author), Mengyu Ren (Author), Jinsi Lin (Author), Chi Liang (Author), Jin Xu (Author), Zhongdao Wu (Author), Xuerong Li (Author), Yan Huang (Author), Xinbing Yu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Clonorchiasis, caused by the infection of Clonorchis sinensis (C. sinensis), is a kind of neglected tropical disease, but it is highly related to cholangiocarcinoma and hepatocellular carcinoma (HCC). It has been well known that the excretory/secretory products of C. sinensis (CsESPs) pl...