Identification immune response genes in psoriasis after treatment with secukinumab

• Main Authors: Jing Wang (Author), Yufang Liu (Author), Yuxin Zhang (Author), Shiyan Wang (Author), Shaomei Kang (Author), Ningyu Mi (Author), Ruxin Li (Author), Yulin Zou (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Secukinumab is a fully human IgG1κ MoAb that selectively binds to IL-17A with high affinity, and it has been proven effective for the treatment of psoriasis. However, the immune response pathways and mechanisms during the treatment are still masked. Therefore, the current study w...