Colon-Targeted eNAMPT-Specific Peptide Systems for Treatment of DSS-Induced Acute and Chronic Colitis in Mouse

• Main Authors: Jae-Sung Kim (Author), Hyo Keun Kim (Author), Minsoo Kim (Author), Sein Jang (Author), Euni Cho (Author), Seok-Jun Mun (Author), Joongho Lee (Author), Dawon Hong (Author), Seokhyun Yoon (Author), Chul-Su Yang (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nicotinamide phosphoribosyl transferase (NAMPT) is required to maintain the NAD⁺ pool, among which extracellular (e) NAMPT is associated with inflammation, mainly mediated by macrophages. However, the role of (e) NAMPT in inflammatory macrophages in ulcerative colitis is insuf...