Peripheral Injection of hUC-MSCs in the Treatment of Acute Liver Failure: A Pre-Clinical Cohort Study in Rhesus Monkeys

• Main Authors: Yuting Zeng (Author), Zhenru Wu (Author), Gen Chen (Author), Guoqiang Liu (Author), Bo Zhang (Author), Yongjie Zhou (Author), Menglin Chen (Author), Rong Yao (Author), Yujun Shi (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Using a toxin-induced lethal acute liver failure (ALF) monkey model, we have recently shown that early peripheral infusion of human umbilical cord mesenchymal stem cells (hUC-MSCs) can alleviate liver damage and improve animal survival by suppressing the activation of circulating monocyt...