Upregulation of HLA Class I Expression on Tumor Cells by the Anti-EGFR Antibody Nimotuzumab

• Главные авторы: Greta Garrido (Автор), Ailem Rabasa (Автор), Cristina Garrido (Автор), Lisset Chao (Автор), Federico Garrido (Автор), Ángel M. García-Lora (Автор), Belinda Sánchez-Ramírez (Автор)
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• Опубликовано: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Предметы: article
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Defining how epidermal growth factor receptor (EGFR)-targeting therapies influence the immune response is essential to increase their clinical efficacy. A growing emphasis is being placed on immune regulator genes that govern tumor - T cell interactions. Previous studies showed an increase in HLA cl...