Cell-Penetrating Penta-Peptides (CPP5s): Measurement of Cell Entry and Protein-Transduction Activity

• Main Authors: Masaru Miyagi (Author), Shigemi Matsuyama (Author), Justine Ngo (Author), Dagmar Hajkova (Author), I-Ju Yeh (Author), Vivian Gama (Author), Jose A. Gomez (Author), Joseph Chen (Author)
• Format: Book
• Published: MDPI AG, 2010-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previously, we developed cell-penetrating penta-peptides (CPP5s). In the present study, VPTLK and KLPVM, two representative CPP5s, were used to characterize the cell-penetration and protein-transduction activities of these small molecules. Various inhibitors of endocytosis and pinocytosis (chlorprom...