Elp1 is required for development of visceral sensory peripheral and central circuitry

• Principais autores: Zariah Tolman (Autor), Marta Chaverra (Autor), Lynn George (Autor), Frances Lefcort (Autor)
• Formato: Livro
• Publicado em: The Company of Biologists, 2022-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Cardiovascular instability and a blunted respiratory drive in hypoxic conditions are hallmark features of the genetic sensory and autonomic neuropathy, familial dysautonomia (FD). FD results from a mutation in the gene ELP1, the encoded protein of which is a scaffolding subunit of the six-subunit El...