Phytomedicine in Disease Management: In-Silico Analysis of the Binding Affinity of Artesunate and Azadirachtin for Malaria Treatment

• 主要な著者: Michael P. Okoh (著者), Rajeev K. Singla (著者), Chijioke Madu (著者), Opeyemi Soremekun (著者), Johnson Adejoh (著者), Lukman A. Alli (著者), Bairong Shen (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In the rural communities of sub-Saharan African (sSA) countries, malaria is being managed using phytocompounds. Artesunate is reported to inhibit Gephyrin E, a central, multi-domain scaffolding protein of inhibitory post-synapses. Neem plant and its metabolites like azadirachtin are being indicated...