Hot and malignant - a case of invasive papillary carcinoma in hyperthyroid patient with hot nodules

Introduction: Malignant thyroid nodules are clinically euthyroid and appear as cold nodules on scintigraphy. Malignancy in hyper-functioning thyroid nodule is rare. Case report: A 48-year-old male with painless swelling on the right side of his neck for the last 4 months complained of feeling hot al...

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Main Authors: Ramesh K. Pandey (Author), Eliza Sharma (Author), Sasmit Roy (Author), Saroj Kandel (Author), Sumit Dahal (Author), Muhammad Rajib Hossain (Author), Marie F. Schmidt (Author), Zewge Shiferaw-Deribe (Author)
Format: Book
Published: Greater Baltimore Medical Center, 2018-07-01T00:00:00Z.
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Summary:Introduction: Malignant thyroid nodules are clinically euthyroid and appear as cold nodules on scintigraphy. Malignancy in hyper-functioning thyroid nodule is rare. Case report: A 48-year-old male with painless swelling on the right side of his neck for the last 4 months complained of feeling hot all the time, sweating and unintentionally losing about 20 pounds. On physical examination, there was a 3-cm mobile, non-tender mass on the right supra-clavicular area biopsy of which was consistent with metastatic papillary carcinoma of thyroid. Neck imaging showed a cystic mass in the right supra-clavicular fossa region, bilateral neck adenopathy and multiple thyroid nodules. Subsequent thyroid radionuclide scans showed three hyper-functioning nodules, which were later demonstrated to be a follicular variant of papillary microcarcinoma. He was treated with total thyroidectomy followed by radioactive iodine thyroid ablation therapy. Conclusion: Physicians need to be aware and vigilant for the possibilities of malignancy in a hyper-functioning thyroid nodule when evaluating any thyroid nodule.
Item Description:2000-9666
10.1080/20009666.2018.1490139