Ferroptosis-Inducing Nanomedicine for Cancer Therapy

Ferroptosis, a new iron- and reactive oxygen species-dependent form of regulated cell death, has attracted much attention in the therapy of various types of tumors. With the development of nanomaterials, more and more evidence shows the potential of ferroptosis combined with nanomaterials for cancer...

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Bibliographic Details
Main Authors: Yang Wang (Author), Tianfu Liu (Author), Xiang Li (Author), Hui Sheng (Author), Xiaowen Ma (Author), Liang Hao (Author)
Format: Book
Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
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100 1 0 |a Yang Wang  |e author 
700 1 0 |a Yang Wang  |e author 
700 1 0 |a Yang Wang  |e author 
700 1 0 |a Tianfu Liu  |e author 
700 1 0 |a Tianfu Liu  |e author 
700 1 0 |a Tianfu Liu  |e author 
700 1 0 |a Tianfu Liu  |e author 
700 1 0 |a Xiang Li  |e author 
700 1 0 |a Xiang Li  |e author 
700 1 0 |a Xiang Li  |e author 
700 1 0 |a Xiang Li  |e author 
700 1 0 |a Hui Sheng  |e author 
700 1 0 |a Xiaowen Ma  |e author 
700 1 0 |a Xiaowen Ma  |e author 
700 1 0 |a Xiaowen Ma  |e author 
700 1 0 |a Xiaowen Ma  |e author 
700 1 0 |a Liang Hao  |e author 
700 1 0 |a Liang Hao  |e author 
700 1 0 |a Liang Hao  |e author 
700 1 0 |a Liang Hao  |e author 
245 0 0 |a Ferroptosis-Inducing Nanomedicine for Cancer Therapy 
260 |b Frontiers Media S.A.,   |c 2021-12-01T00:00:00Z. 
500 |a 1663-9812 
500 |a 10.3389/fphar.2021.735965 
520 |a Ferroptosis, a new iron- and reactive oxygen species-dependent form of regulated cell death, has attracted much attention in the therapy of various types of tumors. With the development of nanomaterials, more and more evidence shows the potential of ferroptosis combined with nanomaterials for cancer therapy. Recently, there has been much effort to develop ferroptosis-inducing nanomedicine, specially combined with the conventional or emerging therapy. Therefore, it is necessary to outline the previous work on ferroptosis-inducing nanomedicine and clarify directions for improvement and application to cancer therapy in the future. In this review, we will comprehensively focus on the strategies of cancer therapy based on ferroptosis-inducing nanomedicine currently, elaborate on the design ideas of synthesis, analyze the advantages and limitations, and finally look forward to the future perspective on the emerging field. 
546 |a EN 
690 |a ferroptosis 
690 |a nanomedicine 
690 |a cancer therapy 
690 |a combination strategies 
690 |a ROS 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pharmacology, Vol 12 (2021) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fphar.2021.735965/full 
787 0 |n https://doaj.org/toc/1663-9812 
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