A kNGR Peptide-Tethered Lipid-Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment

• Үндсэн зохиолчид: Madhu Gupta (Зохиогч), Vikas Sharma (Зохиогч), Kalicharan Sharma (Зохиогч), Anoop Kumar (Зохиогч), Ajay Sharma (Зохиогч), Imran Kazmi (Зохиогч), Fahad A. Al-Abbasi (Зохиогч), Sami I. Alzarea (Зохиогч), Obaid Afzal (Зохиогч), Abdulmalik Saleh Alfawaz Altamimi (Зохиогч), Sachin Kumar Singh (Зохиогч), Gaurav Gupta (Зохиогч), Keshav Raj Paudel (Зохиогч), Philip M. Hansbro (Зохиогч), Kamal Dua (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-07-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The present study aims to design, develop and characterize kNGR (Asn-Gly-Arg) peptide-conjugated lipid-polymer-based nanoparticles for the target-specific delivery of anticancer bioactive(s), i.e., Paclitaxel (PTX). The kNGR-PEG-DSPE conjugate was synthesized and characterized by using spectral anal...