Global experience and future perspectives of minocycline in andrology
<p> <b>S.I. Gamidov, T.V. Shatylko, N.G. Gasanov</b><br> </p> <p> <b>V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russian Federation</b> </p> <p> <i>Antibiotics are commonly used i...
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LCC «Medicine-Inform»,
2019-09-01T00:00:00Z.
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| Summary: | <p> <b>S.I. Gamidov, T.V. Shatylko, N.G. Gasanov</b><br> </p> <p> <b>V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russian Federation</b> </p> <p> <i>Antibiotics are commonly used in andrology for urethritis, prostatitis, and infections of male accessory glands. Antibacterial therapy in andrology has a number of specific features to consider since active ingredient and its derivatives penetrate the prostate and vesicles and affect spermatogenesis, maturation and functional activity of spermatozoa. Tetracyclines are characterized by high efficacy and good safety. Doxycycline is the most commonly used second-generation tetracycline while minocycline is an adequate alternative considering the risks of antibacterial resistance. Although minocycline is little known, it is used in clinical practice for 30 years or even more. Therefore, studies on major effects of minocycline published before 2010 were included on this paper. It was demonstrated that minocycline is non-inferior to other antibiotics for infectious inflammatory disorders caused by Chlamydia and Mycoplasma and, in some aspects, even superior to doxycycline. In addition, some unique properties of this drug (which could yield promising insights into its clinical application and further studies) are discussed.</i> </p> <p> <i><b>Keywords</b>: antibacterial therapy, infections of male accessory glands, Mycoplasma, Chlamydia, minocycline, Minolexin.</i> </p> <p> </p> <p> <i><b>For citation:</b> Gamidov S.I., Shatylko T.V., Gasanov N.G. Global experience and future perspectives of minocycline in andrology. Russian Journal of Woman and Child Health. 2019;2(3):182-186.</i> </p> <i><br> </i><br> <br> |
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| Item Description: | 2618-8430 2686-7184 |