Lipid-based nanosystem of edaravone: development, optimization, characterization and in vitro/in vivo evaluation

• Main Authors: Ankit Parikh (Author), Krishna Kathawala (Author), Chun Chuan Tan (Author), Sanjay Garg (Author), Xin-Fu Zhou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Edaravone (EDR) is a well-recognized lipophilic free radical scavenger for diseases including neurodegenerative disease, cardiovascular disease, and cancer. However, its oral use is restricted due to poor oral bioavailability (BA). The aim of present research was to enable its oral use by developing...