Estrogenic compound attenuates angiotensin II-induced vascular smooth muscle cell proliferation through interaction between LKB1 and estrogen receptor α

• Päätekijät: Sun Ae Kim (Tekijä), Kyung Young Lee (Tekijä), Jae-Ryong Kim (Tekijä), Hyoung Chul Choi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2016-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The prevalence rate of cardiovascular disease is higher for males than females, and estradiol (E2) induces AMP-activated protein kinase (AMPK) activation, which is known to regulate proliferation of VSMC. We identified the estrogenic properties of nordihydroguaiaretic acid (NDGA, a lignan phytoestro...