Mechanism of Antifungal Activity by 5-Aminoimidazole-4-Carbohydrazonamide Derivatives against <i>Candida albicans</i> and <i>Candida krusei</i>

• Main Authors: Fátima Cerqueira (Author), Marta Maia (Author), Carla Gabriel (Author), Rui Medeiros (Author), Sara Cravo (Author), Ana Isabel Ribeiro (Author), Daniela Dantas (Author), Alice Maria Dias (Author), Lucília Saraiva (Author), Liliana Raimundo (Author), Eugénia Pinto (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic mycoses are one major cause of morbidity/mortality among immunocompromised/debilitated individuals. Studying the mechanism of action is a strategy to develop safer/potent antifungals, warning resistance emergence. The major goal of this study was to elucidate the mechanism of action of thre...