Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells

• Main Authors: Tatsuya Tsuda (Author), Masaki Imanishi (Author), Mizuho Oogoshi (Author), Mitsuhiro Goda (Author), Yoshitaka Kihira (Author), Yuya Horinouchi (Author), Yoshito Zamami (Author), Keisuke Ishizawa (Author), Yasumasa Ikeda (Author), Ichiro Hashimoto (Author), Toshiaki Tamaki (Author), Yuki Izawa-Ishizawa (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Arterial calcification, a risk factor of cardiovascular events, develops with differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells. Cyclophilin A (CypA) is a peptidyl-prolyl isomerase involved in cardiovascular diseases such as atherosclerosis and aortic aneurysms, and...