Brain endothelial cell-derived extracellular vesicles with a mitochondria-targeting photosensitizer effectively treat glioblastoma by hijacking the blood‒brain barrier

• Main Authors: Thuy Giang Nguyen Cao (Author), Ji Hee Kang (Author), Su Jin Kang (Author), Quan Truong Hoang (Author), Han Chang Kang (Author), Won Jong Rhee (Author), Yu Shrike Zhang (Author), Young Tag Ko (Author), Min Suk Shim (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma (GBM) is the most aggressive malignant brain tumor and has a high mortality rate. Photodynamic therapy (PDT) has emerged as a promising approach for the treatment of malignant brain tumors. However, the use of PDT for the treatment of GBM has been limited by its low blood‒brain barrier...